Octet® SF3 allows users to generate high-quality binding kinetics and affinity data in a fraction of the time, compared to standard multi-cycle or single-cycle kinetics. Combined with user-designed software, the Octet® SF3 device using surface plasmon resonance provides a robust, high-throughput, low-maintenance solution for the rapid characterization of a wide range of biomolecular interactions.
holds up to three one-liter bottles, comprising of one water and two buffer lines
independently functioning buffer lines, allowing the use of two running buffers to be used during an assay
dedicated water line to minimize the risk of buffer precipitation and blockage formation
Optimized fluidics
optimized fluidic system, specifically designed to minimize potential sources of blockage
system desorb, clean and decontamination protocols ensure maximum system up-time
novel fluidic design results in a strong, robust, low maintenance system
Sample recovery
recovery of precious samples for further analysis can rapidly decrease workflow times
the Octet® SF3 allows the recovery of bound analyte using a predefined Sample Recovery Injection
the same analyte can therefore be re-used for alternative analytical techniques
Thermodynamic and Physiological Measurements
study interactions across a wide range of temperatures to rapidly assess kinetics and affinity of therapeutics at physiological temperatures
in-line buffer degassing prevents air bubble formation and when combined with large syringe volume (700 µl) allows the accurate calculation of dissociation rate constants