CIMmultus® H-Bond

CIMmultus® is a unique and industrially proven line of pre-packaged chromatography monolithic columns with high flow channels, designed to work with large biomolecules such as viruses (AAV, adenovirus, lentivirus, influenza, bacteriophages), nucleic acids (mRNA, pDNA), viral and exosomes. CIMmultus® columns can be used as disposable or single-use columns.

CIMmultus® monoliths are high-resolution chromatography devices designed for multiple scalable purification of complex biological samples. Inside the specially designed housing is a one-piece stationary phase with a homogeneous channel size and surface chemistry. This stationary phase is designed to simplify the transfer of methods from development to production.

Product features:

• multimodal hydrogen donor-acceptor
• working range, pH 2–13
• enables size-based separation of product and contaminants at acidic pH
• elution with increasing salt, pH, or sorbitol
• highly tolerant of salt
• outstanding DNA removal
• unique selectivity for preparative and analytical applications
• sanitizable with 1 M NaOH