Chromatography Columns

Columns play a central role in performing chromatography. Well-packed columns with consistent performance throughout the process design ensure reliable product recovery and separation from contaminants. Proper column design provides increased resolution between peaks, facilitates the packing process for multiple resin types at different bed heights, and enables scalability from process development to full-scale production.

Prepacked Columns

Rapid evaluation of chromatography conditions is essential for determining optimal purification parameters. Condition scouting can be performed on laboratory chromatography systems or automated robotic platforms. PRC prepacked columns and Robo columns for screening are robust tools for fast purification development. Both products come prepacked with materials for ion exchange, mixed-mode, and affinity chromatography. Learn more

Automated Columns

Key column preparation operations, especially packing, are considered high-risk cleanroom events. These risks include human error, failed packing, and the absence of experienced operators, which can result in facility downtime, product or sorbent loss, and inefficient resource utilization. The Resolute Linear software with AutoPak was developed as a direct response to the industry's need for consistent packing through fully automated operations. Learn more

Manual Columns

Process development and production may need to handle various resins, ranging from small to large particles, narrow to wide particle size distributions, and soft to rigid, possibly even fragile particles. Manual columns, combined with a packing station, provide a cost-effective tool for column packing and the ability to develop and optimize packing processes as needed for individual applications and flexibility. Learn more

Hipersep® Prochrom HPLC Chromatography Columns

Our columns meet high design standards, ensuring efficiency and scalability. DAC technology provides repeatability and robustness over time.

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