Prepacked chromatographic columns

A quick check of chromatographic conditions is essential for determining the best purification conditions. Condition scouting can be achieved using laboratory chromatographic systems or automated robotic systems. Especially new functionalities, such as mixed-mode chromatographic materials, require robust screening tools for process development.

Robo Columns for Screening

Robo Columns for Screening are supplied in strips of 8 pre-packed units. The 200 µL units are suited for screening purification conditions and selecting chromatographic materials. The 600 µL units are recommended when longer residence times above 4 minutes are needed (e.g., for evaluating dynamic binding capacities).

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PRC Pre-Packed Columns

PRC Pre-Packed Columns are available in 1 mL and 5 mL formats and are ready to use. The 1 mL columns are recommended for scouting purification conditions, which can be confirmed and further optimized in the 5 mL format with a bed height of 10 cm.

PRC Pre-Packed Chromatography Columns with HyperCel™ STAR AX Salt-Tolerant Anion Exchange Sorbent

The HyperCel™ STAR AX sorbent consists of a rigid cellulose matrix that provides excellent flow properties and generates low backpressure. Available in convenient pre-packed chromatography columns, this product is ideally suited for rapid screening and condition optimization. Two or more columns can be connected in series to increase the column height and more closely model real conditions in pilot-scale or scale-down applications.

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PRC Pre-Packed Chromatography Columns with MEP, HEA, and PPA HyperCel™ Mixed-Mode Sorbents

MEP, HEA, and PPA HyperCel™ sorbents exploit the unique selectivity of robust synthetic ligands to capture proteins or separate them from contaminants. They provide a unique separation mechanism different from conventional methods. All ligands operate predominantly via hydrophobic interaction. This “HIC-like” interaction typically takes place without the addition of lyotropic salt. This pre-packed column format conveniently enables rapid screening and condition optimization.

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PRC Pre-Packed Chromatography Columns with Q and CM Ceramic HyperD™ Ion Exchange Sorbents

Q and CM Ceramic HyperD™ sorbents contain a high-capacity hydrogel polymerized within the gigapores of rigid ceramic beads. These sorbents are available in convenient pre-packed chromatography columns, which are ideal for rapid screening and condition optimization.

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Find the Right Solution for Your Chromatography Process

PRC Pre-Packed Columns and Robo Columns for Screening are robust tools for quick purification development. Both products come pre-packed with ion exchange, mixed-mode, and affinity chromatographic materials.

Column volumesBed heightPrice
Robo Columns for Screening200 and 600 µL10 and 30 mmRequest quote
PRC Pre-Packed Columns1 and 5 mL50 and 100 mmRequest quote